NORTHAMPTON — Numerous standouts across Hampshire County are taking place Saturday to send a message to President Donald Trump and his administration that they should take their hands off American jobs, health care and social services.

The “Hands Off!” national mobilization day is expected to feature protests and demonstrations in all 50 state capitals to rally against actions taken by the president and billionaire Elon Musk, and the executive orders and policies put in place since January.

U.S. Sen. Ed Markey, who will be speaking at the Boston Common Saturday, has called for 100,000 people to show up for that rally. At least one chartered bus will be leaving from Sheldon Field in Northampton for that event, running from 11 a.m. to 3 p.m.

For those who are staying in western Massachusetts, events start at 10:30 a.m. in Amherst, with the Hands Off Amherst rally on the Town Common. At the same time will be the South Hadley Fights Back, at the Town Commons at the intersection of Hadley and College streets, and Haydenville Fights Back at 141 Main St., Haydenville.

Then, starting at noon will be both Easthampton In It Together Standout, at the Easthampton Rotary/ Pulaski Park, and Granby Fights Back, at 70 West State St. In Northampton, another rally is scheduled to start at noon at the intersection of King and Main Street, near the Hampshire County Courthouse.

Jean O’Neil, who has assisted in organizing Haydenville’s rally with Indivisible Williamsburg, a social advocacy group in the town, said she hopes to see as many as 50 people on the lawn of Williamsburg’s town office.

The rally was organized, she said, as a way for people to do something — “or we are going to die,” she said. She encourages participants to make signs advocating for causes close to them that have been threatened as part of Trump’s “avalanche, or deluge,” including impacts to research funding, women’s and trans rights, the climate, Social Security, and other issues.

“We cannot stay passive,” she said Wednesday.

In Franklin County, standouts are scheduled in Greenfield, Orange and Conway.

Leverett resident Ann Ferguson, who helped organize the Greenfield event, said the standouts are a chance for folks to “express their concerns,” whether residents are focused on cuts to social services, the war in Gaza, or the rights of immigrants, women and the LGBTQ community.

“I think both the concert and the standout will help to create the kind of mutual aid and coalitions we need locally to then connect to national resistances to move forward. … It’s really important in this day when we are facing a possible coup and challenge to our democracy,” Ferguson said. “We need to make coalitions to protest and resist because our democracy really depends on the will of the people.”

The Greenfield event will unfold in two parts, with the first kicking off at 3 p.m. at All Souls Church, 399 Main St., with the annual Pete Seeger concert. Along with the new location for the concert, it will also be scripted with Seeger’s words in between songs to introduce the music and its meaning. Two dozen local musicians will take turns performing Seeger’s work.

From there, the event will turn into a singing standout at 6 p.m. on the Greenfield Common with numerous local musicians present, including Annie Hassett, Yosl Kurland and Court Dorsey.